Home » Bursting: The Genesis of Rhythm in the Nervous System by Stephen Coombes
Bursting: The Genesis of Rhythm in the Nervous System Stephen Coombes

Bursting: The Genesis of Rhythm in the Nervous System

Stephen Coombes

Published October 3rd 2005
ISBN : 9789812565068
Hardcover
401 pages
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 About the Book 

Neurons in the brain communicate with each other by transmitting sequences of electrical spikes or action potentials. One of the major challenges in neuroscience is to understand the basic physiological mechanisms underlying the complexMoreNeurons in the brain communicate with each other by transmitting sequences of electrical spikes or action potentials. One of the major challenges in neuroscience is to understand the basic physiological mechanisms underlying the complex spatiotemporal patterns of spiking activity observed during normal brain functioning, and to determine the origins of pathological dynamical states such as epileptic seizures and Parkinsonian tremors. A second major challenge is to understand how the patterns of spiking activity provide a substrate for the encoding and transmission of information, that is, how do neurons compute with spikes? It is likely that an important element of both the dynamical and computational properties of neurons is that they can exhibit bursting, which is a relatively slow rhythmic alternation between an active phase of rapid spiking and a quiescent phase without spiking. This book provides a detailed overview of the current state-of-the-art in the mathematical and computati